The Relationship Between C-Reactive Protein Levels and Visual Acuity in Optic Neuritis: A Study on Disease Severity and Recovery Potential
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Abstract
Optic neuritis (ON) is an inflammatory condition of the optic nerve that can lead to significant visual impairment. C-Reactive Protein (CRP), a marker of systemic inflammation, has been implicated in various inflammatory diseases, including optic neuritis. This study aims to investigate the relationship between CRP levels and visual acuity in ON patients, with a focus on its potential role as a biomarker for disease severity and recovery potential. A cohort of patients diagnosed with optic neuritis was recruited for this study. CRP levels were measured at the time of diagnosis, and visual acuity was assessed at baseline, three months, and six months post-treatment. Statistical analyses were conducted to determine the correlation between CRP levels and visual acuity outcomes. Elevated CRP levels at diagnosis were significantly associated with poorer visual acuity at both three and six months post-diagnosis. A positive correlation was observed between higher CRP levels and increased disease severity, as well as a reduced potential for visual recovery. These findings suggest that CRP may serve as a useful biomarker for predicting both the severity of optic neuritis at onset and the likelihood of visual recovery. This study supports the hypothesis that CRP levels are closely linked to disease severity and recovery outcomes in optic neuritis. Elevated CRP at diagnosis may serve as an early indicator of poor prognosis, highlighting the need for closer monitoring and possibly more aggressive treatment. Future research is warranted to further explore the potential of CRP as a reliable biomarker for optic neuritis and to integrate it with other clinical tools for improved patient management.
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