Comparison of GERD Incidence Rates Based on GERD-Q in Chronic Hepatitis and Decompensated Liver Cirrhosis Patients
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Abstract
This research investigates the incidence of Gastroesophageal Reflux Disease (GERD) in patients with chronic hepatitis and decompensated liver cirrhosis, using the GERD-Q questionnaire as a diagnostic tool. The study aims to compare the prevalence of GERD symptoms in these two liver disease groups and explore the potential impact of GERD on patient management and health outcomes. Data were collected from a cohort of patients diagnosed with chronic hepatitis and decompensated liver cirrhosis, who completed the GERD-Q questionnaire to assess their symptoms. The findings reveal a significantly higher incidence of GERD in patients with decompensated liver cirrhosis compared to those with chronic hepatitis. Furthermore, the study highlights the importance of early detection and treatment of GERD in hepatic patients to prevent complications such as esophagitis and variceal bleeding, which are associated with poor prognosis in liver disease. By identifying the symptom burden in these populations, the research underscores the need for tailored treatment strategies, including pharmacological interventions and lifestyle modifications, to optimize management and improve patient outcomes. This study provides valuable insights into the relationship between GERD and liver disease, offering guidance for clinicians in managing gastrointestinal symptoms in hepatic patients.
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Cassel, C. K., Leipzig, R. M., Cohen, H. J., Larson, E. B., Meier, D. E., Capello, C. F., & Wilson, J. A. P. (2003). Gastroenterologic disorders. Geriatric Medicine: An Evidence-Based Approach, 835–851.
Cho, J. H., Song, D. J., Kang, J. Bin, Lee, D. H., Jin, S., Zhang, C., Zhang, Y., Feng, Z., Zhang, F., & Liu, Z. (n.d.). IP-3_G T he P revalenceof N ontuberculous Mycobacterial Lung Disease with or without Reflux Esophagitis Seoul National University, Bundang Hospital.
Chunlertrith, K., Noiprasit, A., Foocharoen, C., Mairiang, P., Sukeepaisarnjaroen, W., Sangchan, A., & Sawadpanitch, K. (2014). GERD questionnaire for diagnosis of gastroesophageal reflux disease in systemic sclerosis. Clin Exp Rheumatol, 32(Suppl 86), 98–102.
Commisso, A., & Lim, F. (2019). Lifestyle modifications in adults and older adults with chronic gastroesophageal reflux disease (GERD). Critical Care Nursing Quarterly, 42(1), 64–74.
Emmanuel, A., & Inns, S. (2011). Gastroenterology and hepatology. John Wiley & Sons.
Gill, K., Ghazinian, H., Manch, R., & Gish, R. (2016). Hepatitis C virus as a systemic disease: reaching beyond the liver. Hepatology International, 10, 415–423.
Jones, R. T. (2016). Clinical approach to gastro-oesophageal reflux in idiopathic pulmonary fibrosis. Newcastle University.
Kahrilas, P. J. (2003). GERD pathogenesis, pathophysiology, and clinical manifestations. Cleveland Clinic Journal of Medicine, 70(5), S4.
Kaltenbach, T., Crockett, S., & Gerson, L. B. (2006). Are lifestyle measures effective in patients with gastroesophageal reflux disease?: an evidence-based approach. Archives of Internal Medicine, 166(9), 965–971.
Katzka, D. A., & Kahrilas, P. J. (2020). Advances in the diagnosis and management of gastroesophageal reflux disease. Bmj, 371.
Khalaf, M., Castell, D., & Elias, P. S. (2020). Spectrum of esophageal motility disorders in patients with liver cirrhosis. World Journal of Hepatology, 12(12), 1158.
Kim, W. O. (2012). Institutional review board (IRB) and ethical issues in clinical research. Korean Journal of Anesthesiology, 62(1), 3.
Li, D., Sedano, S., Allen, R., Gong, J., Cho, M., & Sharma, S. (2019). Current treatment landscape for advanced hepatocellular carcinoma: patient outcomes and the impact on quality of life. Cancers, 11(6), 841.
Okushin, K., Takahashi, Y., Yamamichi, N., Shimamoto, T., Enooku, K., Fujinaga, H., Tsutsumi, T., Shintani, Y., Sakaguchi, Y., & Ono, S. (2015). Helicobacter pylori infection is not associated with fatty liver disease including non-alcoholic fatty liver disease: a large-scale cross-sectional study in Japan. BMC Gastroenterology, 15, 1–10.
Roehlen, N., Crouchet, E., & Baumert, T. F. (2020). Liver fibrosis: mechanistic concepts and therapeutic perspectives. Cells, 9(4), 875.
Rosselli, M., MacNaughtan, J., Jalan, R., & Pinzani, M. (2013). Beyond scoring: a modern interpretation of disease progression in chronic liver disease. Gut, 62(9), 1234–1241.
Rudralingam, V., Footitt, C., & Layton, B. (2017). Ascites matters. Ultrasound, 25(2), 69–79.
Saberifiroozi, M. (2017). Improving quality of care in patients with liver cirrhosis. Middle East Journal of Digestive Diseases, 9(4), 189.
Samonakis, D. N., Koulentaki, M., Coucoutsi, C., Augoustaki, A., Baritaki, C., Digenakis, E., Papiamonis, N., Fragaki, M., Matrella, E., & Tzardi, M. (2014). Clinical outcomes of compensated and decompensated cirrhosis: A long term study. World Journal of Hepatology, 6(7), 504.
Shaheen, N. J., Hansen, R. A., Morgan, D. R., Gangarosa, L. M., Ringel, Y., Thiny, M. T., Russo, M. W., & Sandler, R. S. (2006). The burden of gastrointestinal and liver diseases, 2006. Official Journal of the American College of Gastroenterology| ACG, 101(9), 2128–2138.
Spechler, S. J. (2013). Barrett esophagus and risk of esophageal cancer: a clinical review. Jama, 310(6).
Strobl, J., Cave, E., & Walley, T. (2000). Data protection legislation: interpretation and barriers to research. Bmj, 321(7265), 890–892.
Wijarnpreecha, K., Panjawatanan, P., Thongprayoon, C., Jaruvongvanich, V., & Ungprasert, P. (2017). Association between gastroesophageal reflux disease and nonalcoholic fatty liver disease: A meta-analysis. Saudi Journal of Gastroenterology, 23(6), 311–317.
Wolfe, M. M., & Sachs, G. (2000). Acid suppression: optimizing therapy for gastroduodenal ulcer healing, gastroesophageal reflux disease, and stress-related erosive syndrome. Gastroenterology, 118(2), S9–S31.
Yuksel, E. S., & Vaezi, M. (2012). Extraesophageal manifestations of gastroesophageal reflux disease: cough, asthma, laryngitis, chest pain. Swiss Medical Weekly, 142(1112), w13544–w13544.
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